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The effect of Medilac on the symptoms and gut microbiota in diarrhea-dominated irritable bowel syndrome

The effect of Medilac on the symptoms and gut microbiota in diarrhea-dominated irritable bowel syndrome: a clinical trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034041
Enrollment
Unknown
Registered
2020-06-21
Start date
2020-12-01
Completion date
Unknown
Last updated
2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable bowel syndrome

Interventions

Health control:Without intervention
IBS-D:Without intervention
IBS-D treated with Medilac:Medilac

Sponsors

Union Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with IBS-D were diagnosed according to Rome III standard; 2. Patients between the ages of 18-65 years old, regardless of gender; 3. Patients suitable for drug treatment; 4. Patients who voluntarily accept the treatment of the drug and sign the informed consent form, the informed consent process complies with the relevant provisions of GCP.

Exclusion criteria

Exclusion criteria: 1. Those patients with general or special contraindications treated by meichang'an; 2. Patients with serious primary diseases, such as cardiovascular, cerebrovascular, liver, kidney, hematopoietic system, hyperthyroidism, diabetes, or serious diseases (such as tumor) and psychosis that affect their survival. 3. Pregnant or preparing pregnant or lactating women. 4. Patients suspected or with a history of alcohol and drug abuse. 5. Patients with cognitive impairment who can not give full informed consent.

Design outcomes

Primary

MeasureTime frame
Gut microbiota;

Secondary

MeasureTime frame
IBS-SSS;Abdominal symptom score;IBS-QOL;

Countries

China

Contacts

Public ContactXiaohua Hou

Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

houxh@hust.edu.cn+86 13035143646

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026