General anesthesia patients
Conditions
Interventions
Group 1:Remimazolam Tosilate for Injection
Group 2:propofol
Sponsors
The First People's Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) 18 <= age <= 65, gender unlimited; 2) The operation time was less than 2 hours; 3) ASA score is grade I or II; 4) 18 kg/m2 < BMI < 30kg/m2; 5) Clearly understand and voluntarily participate in the study, and sign the informed consent form by himself / herself.
Exclusion criteria
Exclusion criteria: 1) Keywords emergency operation; hypovolemia, shock or coma; 2) Besides general intravenous anesthesia, other anesthesia methods should be combined, such as inhalation anesthesia, epidural anesthesia and subarachnoid anesthesia; 3) Keywords infective heart disease such as myocarditis or endocarditis; sepsis; 4) Uncontrolled hypertension, diabetes, heart failure, etc.; 5) Abnormal liver function, AST and / or ALT >= 2.5 * ULN, TBIL >= 1.5 * ULN; 6) Renal function was abnormal, urea or urea nitrogen >= 1.5 * ULN, creatinine was higher than the upper limit of normal value; 7) Patients with mental system diseases (schizophrenia, mania, bipolar disorder, insanity, etc.) and long-term history of taking psychotropic drugs and cognitive dysfunction; 8) Pregnant or lactating women; 9) Allergic or contraindicated to benzodiazepines, opioids, propofol, muscle pines and other drugs; 10) Other circumstances in which the researchers consider it inappropriate to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of anesthesia and sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anesthesia induction time;Incidence of hypotension during anesthesia induction;Incidence of hypotension during anesthesia;Recovery time of anesthesia;Incidence of intraoperative awareness; | — |
Countries
China
Contacts
Public ContactXiaobao Zhang
Department of Anesthesiology, the First People's Hospital of Lianyungang
Outcome results
None listed