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Comparison of GnRH agonist versus GnRH antagonist protocol on the cumulative live birth rate in POSEIDON subgroup 3 patients: a randomized controlled trial

Comparison of GnRH agonist versus GnRH antagonist protocol on the cumulative live birth rate in POSEIDON subgroup 3 patients: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034025
Enrollment
Unknown
Registered
2020-06-21
Start date
2020-06-20
Completion date
Unknown
Last updated
2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility

Interventions

GnRHa:Triptorelin (Dabipramine 0.1mg/ day) will be routinely administered subcutaneously for 14 days after ovulation
GnRHant group:Give Cetrotide 0.25mg/day when about 12 mm of the follicle diameter until HCG trigger day

Sponsors

Reproductive medicine center of Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Patients with low ovarian reserve and young age who received IVF / ICSI treatment in our center; 2. According to the Poseidon 3 subgroup standard, the age of patients was less than 35 years old, and the ovarian reserve was low (AFC < 5 or AMH < 1.2ng / ml); 3. The 1st-3rd IVF / ICSI treatment cycle.

Exclusion criteria

Exclusion criteria: 1. Patients with more than three cycles of ovulation induction; 2. Patients with severe endometriosis; 3. Hydrosalpinx patients; 4. Patients with endometrial adhesions and malformations; 5. Patients with chromosomal abnormalities.

Design outcomes

Primary

MeasureTime frame
cumulative live birth rate per started cycle;

Countries

China

Contacts

Public ContactLai Qiaohong

Reproductive medicine center of Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology

lqh74@126.com+86 13995632591

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026