Clinical research on the effectiveness and mechanism of multi-domain computerized cognitive training to mild cognitive impairment

Clinical research on the effect of cognitve assessments and training all-in-one machine

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000034012

Enrollment

Unknown

Registered

2020-06-21

Start date

2020-07-04

Completion date

Unknown

Last updated

2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitve impairment

Interventions

Experimental group:computerized cognitive training

control group:healthy education,keeping original lifestyle

Eligibility

Sex/Gender

All

Age

50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. meet the diagnosis criteria of MCI; 2. Montreal Cognitive Assessment (MoCA) score of = 25 and one point will be added to correct the educational effect for patients with less than twelve years of education 3. aged 50 to 85 years old; 4. literate in Han Chinese; 5. the grade of Global Deterioration Scale (GDS)from 2 to 3 6. right handedness 7. be willing to join and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. uncontrolled hypertension (systolic blood pressure over 160 mmHg or diastolic blood pressure over 100 mmHg after taking medicine); 2. diagnosed as dementia or other psychiatric disease according to the fifth edition of the diagnostic and statistical manual of mental disorders (DSM-V) ; 3. history of alcohol or drug abuse; 4. history of psychiatric disorders; 5. other system diseases that may cause the noncooperation with intervention and evaluation (i.e. severe organ failure, myocardial infarction or musculoskeletal system diseases); 6. the score of Hamilton Depression scale(HAMD)>10; 7. the score of Hachinski Ischemic Scale (HIS) = 5; 8. had taken tranquilizers, antidepressants, psychostimulants or any other drugs that may affect the cognitive function in last two weeks; 9. be taking part in other studies that may affect the result of this study 10. any contraindication to MRI (eg. pacemaker, fever, fixed denture, metal implant, claustrophobia etc.).

Design outcomes

Primary

Measure	Time frame
Montreal Cognitive Assessment;Auditory verbal learning test;	—

Secondary

Measure	Time frame
Trail Making Test-B;Stroop Color-word Test;Digit symbol substitution test;Rey-Osterrieth complex figure test;Alzheimer's Disease Assessment Scale- Cognitive subscale;Magnetic Resonance Image;	—

Countries

China

Contacts

Public ContactCai Sufang

Affiliated Rehabilitation Hospital of Fujian University of Traditional Chinese Medicine

178870666@qq.com+86 158599019854

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026