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The characteristics of urinary microbiota in female patients with overactive bladder / urgency incontinence (OAB / UUI) and its correlation with drug treatment outcome

The characteristics of urinary microbiota in female patients with overactive bladder / urgency incontinence (OAB / UUI) and its correlation with drug treatment outcome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034007
Enrollment
Unknown
Registered
2020-06-21
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

overactive bladder

Interventions

OAB/UUI group:N/A

Sponsors

Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: OAB/UUI group: 1. adult female patients aged >=18 years; 2. diagnosed with OAB or UUI; 3. patients agree to participate in this study and sign informed consent. Health group: 1. adult female patients aged >=18 years; 2. diagnosed without any disease of urinary system; 3. patients agree to participate in this study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. diagnosed with urinary tract infection by urine routine test or standard cultivation; 2. with previous history of bladder or urethral surgery; 3. with the history of antibiotic use in the last 2 weeks; 4. have taken drugs that affect the function of lower urinary tract in the past 1 week; 5. diagnosed with neurogenic bladder; 6. diagnosed with interstitial cystitis; 7. lower urinary tract symptoms was caused by drug abuse (such as ketamine-associated cystitis); 8. chemotherapy drugs cause chemical cystitis (such as cyclophosphamide); 9. with previous history of radiotherapy; 10. patients have a definite urinary system disease (such as urinary tuberculosis, urinary stones, etc.); 11. during pregnancy, lactation and menstruation; 12. pelvic organ prolapse> II degree. Health group: 1. diagnosed with urinary tract infection by urine routine test or standard cultivation; 2. with previous history of bladder or urethral surgery, chemotherapy and radiotherapy; 3. with the history of antibiotic use in the last 2 weeks; 4. diagnosed with disease of urinary system; 5. during pregnancy, lactation and menstruation; 6. anatomical abnormality of urinary system; 7. pelvic organ prolapse> II degree.

Design outcomes

Primary

MeasureTime frame
OABSS scale score;

Secondary

MeasureTime frame
VAS score;

Countries

China

Contacts

Public ContactWu Peng

Nanfang Hospital, Southern Medical University

doctorwupeng@gmail.com+86 13926467094

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026