The effect of intravenous esmketamine on relieving postoperative pain and agitation in children

Effect of S-ketamine on postoperative pain sensitivity in children with preoperative chemotherapy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000033994

Enrollment

Unknown

Registered

2020-06-20

Start date

2020-07-01

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

Group 1:Preoperative chemotherapy and intravenous esmketamine

Group 2:Preoperative chemotherapy

control group:intravenous normal saline

Eligibility

Sex/Gender

All

Age

1 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 1-12; 2. ASA class I-III patients; 3. Patients undergoing elective surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to esmketamine; 2. Patients who used other analgesics 48 hours before operation; 3. Patients with BMI > 30; 4. Patients with cardiovascular disease or other serious systemic diseases; 5. Other conditions not suitable for the study.

Design outcomes

Primary

Measure	Time frame
Pain threshold;FLACC score;agitation score;	—

Countries

China

Contacts

Public ContactZhou Siyi

Department of Anesthesia, Shanghai Children's Medical Center

shirley_zsy@126.com+86 21-38627330

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026