Advanced gastric cancer, ovarian cancer, breast cancer and bladder cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with advanced gastric cancer, ovarian cancer, breast cancer and bladder cancer confirmed by histopathology; 2. Patients who can collect malignant pleural and ascites samples and separate sufficient tumor cells; 3. CT / MRI can be used to evaluate the curative effect of patients with objective tumor focus meeting the criteria of RECIST 1.1; 4. Patients with KPS >= 60 and expected survival time >= 3 months; patients who can tolerate chemotherapy and targeted treatment according to comprehensive evaluation, and who need radiotherapy, should be after chemotherapy and targeted treatment to avoid affecting the effect of the former. 5. Patients who voluntarily participate and sign informed consent have good compliance and can actively treat and cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with unplanned reoperation after operation; 2. Patients with other tumors or a second tumor were found during the treatment, which interfered with the study; 3. Blood biochemical examination indicates that the patient is not suitable to continue chemotherapy or the chemotherapy is delayed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall response rate;overall survival;progression-free survival; | — |
Countries
China
Contacts
The First Affiliated Hospital, College of Medicine, Zhejiang University