cervical cancer
Conditions
Interventions
experimental group:Paclitaxel was intravenously administered and cisplatin trans-uterine arterial administered C followed by transcatheter embolization with gelatin sponge particles
Sponsors
International Peace Maternal and Child Health Hospital affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Cervical cancer stage IB3,IIA2 and IIB; (2) Aged between 20 to 70 years; (3) Tumors were >= 4 cm in diameter on magnetic resonance imaging (MRI); (4) Eastern Cooperative Oncology Group (ECOG) performance status of 0-2 (5) Adequate bone marrow reserve(hemoglobin >= 9 g/dl, absolute neutrophil count (ANC) >= 2000/mm3, platelet count >= 100,000 /mm3); (6) Adequate renal, hepatic, and cardiac functions; (7) All patients provided written informed consent prior to enrollment.
Exclusion criteria
Exclusion criteria: (1) Previously received chemotherapy, radiotherapy and other related treatment (2) Pregnant patients (3) Those who plan to maintain fertility (4) Previously received subtotal hysterectomy (5) Uncontrolled comorbidities (6) History of thrombotic events.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical responses;pathological responses; | — |
Secondary
| Measure | Time frame |
|---|---|
| safety;Radical surgery rate; | — |
Countries
China
Contacts
Public ContactYudong Wang
International Peace Maternal and Child Health Hospital affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed