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Effectiveness and Safety of Compound Lidocaine Cream Combined with Oxycodone for the Prevention of Catheter-Related Bladder Discomfort in Patients Undergoing Transurethral Resection of Bladder Tumor

Effectiveness and Safety of Compound Lidocaine Cream Combined With Oxycodone for the Prevention of Catheter-Related Bladder Discomfort in Patients undergoing Transurethral Resection of Bladder Tumor

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033915
Enrollment
Unknown
Registered
2020-06-16
Start date
2020-06-17
Completion date
Unknown
Last updated
2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Catheter-related Bladder Discomfort

Interventions

Group 3:compound lidocaine cream
Group 2:Oxycodone 0.05mg/kg
Group 1:compound lidocaine cream combined with oxycodone

Sponsors

Zhongshan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. 18-85-year-old male patients who want to undergo TURBT under selective general anesthesia and need to have catheterization during the operation; 2. Patients with ASA grade 1-3; 3. Patients willing to participate in the clinical trial and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who are allergic to the relevant drugs used in the study; 2. Those patients who use sedative and analgesic drugs for a long time; 3. Patients with chronic hepatorenal insufficiency; 4. Patients with serious cardiovascular diseases, such as uncontrolled hypertension, serious coronary heart disease, heart failure, serious arrhythmia, etc; 5. Patients with mental illness or cognitive dysfunction, no or limited capacity for behavior; 6. Patients with lower urinary tract infection or obstruction and bladder irritation.

Design outcomes

Primary

MeasureTime frame
The incidence and severity of immediate postoperative CRBD;

Secondary

MeasureTime frame
Incidence and severity of CRBD at 24h, 48h after operation;VAS;RAMSAY;

Countries

China

Contacts

Public ContactCang Jing

Zhongshan Hospital Affiliated to Fudan University

cangjing_zs@sina.com+86 13916010421

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026