Healthy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Local healthy people aged 18-65 years can be both male and female. 2. BMI index is between 19-35 kg/m2 (inclusive).
Exclusion criteria
Exclusion criteria: 1. Patients with chronic / infectious / major diseases diagnosed by the hospital, or with respiratory and / or gastrointestinal diseases, as well as serious abnormalities in physical examination; 2. Any abnormal physical condition or medical condition affecting the gastrointestinal tract or the administration of experimental prebiotic products; 3. Patients who have undergone abdominal or intestinal surgery within one year. 4. Patients who use drugs related to digestive tract diseases within 2 weeks, such as antispasmodic drugs, cathartic drugs, antidiarrheal drugs and other drugs that affect intestinal peristalsis. 5. Patients who currently or recently (within 1 month) use microecological agents (probiotics / prebiotics / synbiotics), dietary supplements, Chinese herbal medicines, or take large doses of vitamins or minerals; 6. Those patients who currently or recently (1 month) or long-term use antibiotics; 7. Patients who have long-term consumption of yogurt, cheese, probiotic drinks, fermented products and other probiotic foods; 8. Lactose intolerant patients; 9. Those who have significant changes in their eating habits in the near future (within one month), such as starting to eat a diet rich in fiber, etc.; 10. Women who are pregnant, breast-feeding or wish to be pregnant; 11. Subjects with convulsion symptoms or mental history; 12. Subjects of other clinical studies at present or in the near future (within one mo nth).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composition and abundance of intestinal microflora in feces;Fecal Mategenome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal short-chain fatty acids;Absolute quantitative of fecal flora; | — |
Countries
China
Contacts
School of Food Science and Technology, Jiangnan University