Postoperative delirium
Conditions
Interventions
control group:normal saline
Sponsors
Xinhua Hospital Affilated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with age >= 65 years old, regardless of gender; 2. Patients who meet the indication of MVD operation under general anesthesia; 3. Agree to participate in the trial, and the patient or his guardian with legal significance shall sign the informed consent before the trial.
Exclusion criteria
Exclusion criteria: 1. Patients with MMSE score < 23; 2. Patients with liver and kidney dysfunction; 3. Patients with central nervous system diseases; 4. Patients who have a history of mental illness and take sedatives and antidepressants for a long time; 5. Patients with a history of alcohol and drug abuse; 6. Patients with serious systemic diseases, especially circulatory diseases, such as myocardial infarction, heart failure, unstable angina, history of sinobradycardia; 7. Patients who can not tolerate the experiment or cooperate with the examination due to various reasons, various aphasia, audio-visual dysfunction, etc; 8. Patients known to be allergic to huperzine A; 9. Patients who participated in other clinical trials within 3 months before the start of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium rating scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| CAM-ICU;MMSE;NPI; | — |
Countries
China
Contacts
Public ContactShiting Li
Xinhua Hospital Affiliated to School of Medicine, Shanghai Jiaotong University
Outcome results
None listed