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Gut Microbial Composition and Serum Metabolites Profile Linked to Atherosclerosis Severity and Major Adverse Cardiac Event Risk

Alterations in the gut microbiome and metabolism with coronary artery disease severity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000033897
Enrollment
Unknown
Registered
2020-06-15
Start date
2016-12-01
Completion date
Unknown
Last updated
2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Interventions

CAD group:None
Control group:None

Sponsors

Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: We recruited Chinese patients who underwent elective coronary angiography at Peking Union Medical College Hospital and exhibited >=50% stenosis in at least one main coronary artery. The subject's age range must be between 50-75 years old and non-vegetarian.

Exclusion criteria

Exclusion criteria: Subjects were excluded if they had gastrointestinal diseases, malignant tumours, autoimmune disorders, infectious diseases, renal dysfunc- tion (severe renal disease creatinine > 3.0 mg/dl), a history of gastrointestinal surgery in the previous year or were ad- ministered antibiotics for more than 3 days in the previous 3 months.

Design outcomes

Primary

MeasureTime frame
Gut micobiome variation;Serum Metabolomics Profiile;—

Countries

China

Contacts

Public ContactShuyang Zhang

Peking Union Medical College Hospital

shuyangzhang103@nrdrs.org+86 10 69156802

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026