myasthenia gravis
Conditions
Interventions
robotic group:robotic subxiphoid extended thymectomy
thoracoscopic group:video-assisted thoracoscopic subxiphoid extended thymectomy
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
No minimum to 75 Years
Inclusion criteria
Inclusion criteria: (1) patients with myasthenia gravis graded as MGFA class II-IV (myathenia gravis foundation of america); (2) positive serum anti-acetylcholine receptor antibodies (AchR Ab); (3) patients aged <=75 years; (4) myasthenia gravis complicated with thymoma of Masaoka-Koga stage I, II or III.
Exclusion criteria
Exclusion criteria: (1) myasthenic weakness requiring intubation (MGFA Class V); (2) daily usage of pyridostigmine >=360mg; (3) patients with impaired cardiac, kidney, liver or lung function and had a great risk; (4) patients who refuse to undergo R-SET or VAT-SET.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraoperative blood loss;Degree of tumor resection;postoperative score of Borg-CR10;score of NASA-TLX;Postoperative drainage volume;postoperative pain score;length of surgery;length of drainage tube;Myasthenia Gravis Composite(MGC);postoperative length of stay;postoperative complications;change of postoperative drug dose;MGFA Postintervention Status;removal times of the endoscope for external cleaning; | — |
Countries
China
Contacts
Public ContactWang Yun
Department of Thoracic Surgery, West China Hospital, Sichuan University
Outcome results
None listed