Postoperative fatigue (POF)
Conditions
Interventions
Intravenous anesthesia group (Group P):Narcotization was conducted under EEG monitoring. TCI propofol (2.5 -- 3.5 g/ mL) and Remifentanil (1.5-2.5ng/ml) was administered to maintain Narcotrend at D0-2
Combined anesthesia group (Group S):Narcotization was conducted under EEG monitoring.Inhalation of 1.5-2.5% sevoflurane, minimum effective alveolar concentration (MAC) was maintained at 0.7, TCI remif
Sponsors
The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
45 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1. Over 45 years old and under 74 years old; 2. American Society of anesthesiologists (ASA) grade: I-II; 3. Patients who have indications for total hysterectomy and decide to perform minimally invasive surgery under laparoscope; 4. Obtain the informed consent of the patient and / or legal guardian, and sign the informed consent;
Exclusion criteria
Exclusion criteria: 1. Patients who received emergency operation within 24 hours after admission; 2. The patients had fatigue symptoms before operation, i.e. visual analogue scale > 5 points; 3. The patient has communication disorder (language disorder, mental disorder) and can't cooperate; 4. If the patient is allergic to a certain drug in the anesthesia program, other drugs should be used instead;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identity-Consequences Fatigue Scale-10, ICFS-10;Visual simulation scale, VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative grip strength examination;Time of first postoperative ambulation;Postoperative anal exhaust time;length of patient stay; | — |
Countries
China
Contacts
Public ContactXue Bai
The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Outcome results
None listed