Aortic lesion
Conditions
Interventions
Group 2:moderate hypothermia
Group 1:mild hypothermia
Sponsors
Department of Cardiovascular Surgery, General Hospital of Northern Theater Command
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 80 years; 2. Patients with Stanford type A aortic dissection or arch aneurysm; 3. Patients without aortic valve disease or pericardial tamponade; 4. Patients without nervous system diseases; 5. Patients without organ damage confirmed by abdominal CT or B-ultrasound; 6. Patients who had the first heart operation; 7. Patients without congenital heart history; 8. Those patients who have good compliance and can cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with two or more cardiac operations; 2. Patients with heart operation accompanied by other body parts operation; 3. Patients with liver and kidney function damage (the detection result is more than 3 times of the upper limit of normal value) and operation contraindications; 4. Patients with other diseases requiring radiotherapy, chemotherapy and long-term hormone treatment; 5. Patients who have participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of liver, kidney and brain complications in patients during perioperative period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Days of hospital stay following surgery;Days of ICU stay;PCT, IL-6, hsCRP;extracorporeal circulation duration;Aortic occlusion duration;Ventilator assist duration;Perioperative blood transfusion; | — |
Countries
China
Contacts
Public ContactHui Jiang
Department of Cardiovascular Surgery, General Hospital of Northern Theater Command
Outcome results
None listed