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Effect of oral alkali supplementation on residual renal function in peritoneal dialysis patients without metabolic acidosis

Effect of oral alkali supplementation on residual renal function in peritoneal dialysis patients without metabolic acidosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033847
Enrollment
Unknown
Registered
2020-06-14
Start date
2021-01-01
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Residual renal function in peritoneal dialysis

Interventions

High-dose trial group:Oral sodium bicarbonate 2g/d
Low-dose trial group:Oral sodium bicarbonate 1g/d
High-dose control group:Oral placebo 2g/d
Low-dose control group:Oral placebo 1g/d

Sponsors

Shaoxing Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Maintenance peritoneal dialysis patients with serum bicarbonate level between 22-29mmol / L

Exclusion criteria

Exclusion criteria: 1. Patients with history of hemodialysis or kidney transplantation; 2. Taking 5 or more antihypertensive drugs; 2. Patients whose urine volume was less than 200 ml / day in 4 hours; 3. Patients taking bicarbonate orally within 2 weeks before admission.

Design outcomes

Primary

MeasureTime frame
Residual renal function;—

Countries

China

Contacts

Public ContactHuang Yiqi

Shaoxing Second Hospital

hyq15925803800@163.com+86 15925803800

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026