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A multicenter study for safety, feasibility of 30 to 33 + 6 weeks premature babies early full amount breastfeeding in NICU

A multicenter study for safety, feasibility of 30 to 33 + 6 weeks premature babies early full amount breastfeeding in NICU

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033823
Enrollment
Unknown
Registered
2020-06-14
Start date
2020-07-01
Completion date
Unknown
Last updated
2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature infants breastfeeding

Interventions

Control group:no intervention (Primary feeding programmes at the centres)
Intervention group:the intervention group adopted the early full-volume breast-feeding (start milk at birth within 4 hours with an increase rate of -30ml/kg/d)

Sponsors

The University of Hong Kong-Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 30-33 + 6 weeks gestational age, singletons, prenatal activity after completed the full course of hormone, good vitality after birth (fetal to newborns transition smoothly, without history of asphyxia recovery, normal Apgar score), family members actively cooperate with two weeks (before birth parents with children with skin contact time average of 4 h/day or higher), can provide enough breastfeeding (prenatal milk mission and postnatal mammary by professional lactation consultant guide), and support exclusive breastfeeding.

Exclusion criteria

Exclusion criteria: 1. Congenital malformations or chromosomal abnormalities disease; 2. Symptomatic chorionic inflammation (mother in childbirth fever, elevated white blood cell count, premature rupture of membranes, four high-risk factors such as amniotic fluid smell three or above) in severe hypotension or shock to fluid resuscitation; 3. Cardiac or vascular active drug rescue; 4. Apgar score < 8; 5. Childbirth need chest compression or use adrenaline recovery; 6. Within 24 hours of birth children need to continue to use ventilator support; 7. Newborn less than gestational age.

Design outcomes

Primary

MeasureTime frame
weight;length;head circumference;risk of NEC;Time to apply TPN;

Secondary

MeasureTime frame
Length of stay;

Countries

China

Contacts

Public ContactZhang Qianshen

The University of Hong Kong-Shenzhen Hospital

zhangqianshen@hku-szh.org+86 13500052619

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026