Study on the mechanism of post-stroke cognitive impairment based on iTBS under neuroimaging and event-related potentials

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000033818

Enrollment

Unknown

Registered

2020-06-13

Start date

2020-07-01

Completion date

Unknown

Last updated

2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Group A:iTBS

Group B:sham-iTBS

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The first stroke, the course of disease is 1-6 months; 2. Right-handed; 3. Aged 18-70 years; 4. Mild to moderate cognitive impairment, MoCA score 11-26; 5. No serious aphasia and can complete the cognitive test; 6. Stable vital signs and no progressive neurological symptoms; 7. Volunteer to participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Complete injury of the left frontal lobe; 2. There are metal implants in the body, pacemakers or skull defects can not be treated with rTMS; 3. Previous brain tumors, brain trauma, history of epilepsy and risk of seizures; 4. There is a decrease in cognitive function before stroke; 5. Any neuropsychiatric illness and obvious affective disorder can affect the test results; 6. Any other factors affecting assessment and treatment.

Design outcomes

Primary

Measure	Time frame
Montreal Cognitive Assessment;	—

Secondary

Measure	Time frame
Stroop test;Go/No Go test;1-back test;N2;P300;N450;BDNF genetic polymorphism;fMRI;	—

Countries

China

Contacts

Public ContactYao Liqing

The Second Affiliated Hospital of Kunming Medical University

yaoliqing98731@163.com+86 13529202383

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026