bone cancer pain
Conditions
Interventions
transcriptomics of metastatic bone pain group vs non bone pain group:N/A
Sponsors
Department of Anesthesiology, the First Af?liated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Reaching the age of 18 years; 2. Histologically or cytologically confirmed lung adenocarcinoma; 3. The biopsy of bone metastasis in the spine comes from lung cancer /with typical imaging manifestation of bone metastasis, that is, MRI/PET-CT/ bone biopsy was required for the diagnosis of the localized lesions, while PET-CT/CT/ X-ray /MR diagnosis was required for the extensive lesions.
Exclusion criteria
Exclusion criteria: 1. Radiotherapy was applied to the tumor site or pain site within the 1 month; 2. Non-cancerous pain or pain caused by non-bone metastases; 3. Obvious hepatic and renal insufficiency;Acute/chronic infectious diseases; 4. Inability to accurately describe the site of pain and to rate pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gene expression level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diagnosis time of lung adenocarcinoma; Time and site of bone metastasis; Current treatment options for tumors; The duration of the pain; The time of onset of explosive pain; Drug use (type, dosage, duration); Visual simulation score for pain;The general condition of the patient;Vital signs (temperature, respiration, heart rate, blood pressure);Laboratory examination and auxiliary examination; | — |
Countries
China
Contacts
Public ContactDou yunling
The First Affliated Hospital of Sun Yat-Sen University
Outcome results
None listed