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Research on the mechanism of botulinum toxin relieving spasticity in children with cerebral palsy

Research on the mechanism of botulinum toxin relieving spasticity in children with cerebral palsy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033800
Enrollment
Unknown
Registered
2020-06-13
Start date
2020-06-22
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral palsy

Interventions

Sponsors

Guangzhou Women and Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the criteria of diagnosis and classification of spastic cerebral palsy; 2. Patients aged 2-10 years; 3. Patients with significant spasm of hand and lower extremity, GMFCS level I-III, MAS score at least greater than level 2; 4. Parents can cooperate with the research and sign the consent.

Exclusion criteria

Exclusion criteria: 1. Patients with other diseases unrelated to cerebral palsy and uncontrolled seizures; 2. The patients had fixed contracture or deformity in the upper and lower limbs, and they had received orthopedic operation before the study or prepared to receive orthopedic operation during the study; 3. patients who had been treated with botulinum toxin within the first 6 months of this study.

Design outcomes

Primary

MeasureTime frame
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Countries

China

Contacts

Public ContactKaishou Xu

Guangzhou Women and Children's Medical Center

xksyi@126.com+86 18902268610

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026