Cancer pain
Conditions
Interventions
treatment group:tetralogy of viable bifidobacterium tablets
control group:No
Sponsors
Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The clinical manifestations (symptoms, signs), auxiliary examination (tumor markers and other serological indicators) and pathological examination (tissue biopsy) of the patients were confirmed as cancer; 2. Patients aged between 18-75 years; 3. Patients with moderate or severe pain with NRs >= 4; 4. Patients who agree to participate in the trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute abdomen such as perforation of digestive tract, acute pancreatitis and acute intestinal obstruction; 2. Patients with poor general conditions (such as severe hemiplegia, long-term bed rest, malnutrition, bad liquid quality, etc.); 3. Patients with liver and kidney dysfunction; 4. Patients who participate in any other research treatment that may have an impact on pain intensity; 5. Exclude the patients who may affect the distribution of intestinal flora in the near future (such as the application of probiotics, antibiotics, acute infectious diseases, etc.); 6. Patients with a history of drug abuse, addiction or serious alcohol abuse; 7. Patients with opioid allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora;Inflammatory cytokines;C-reactive protein;Erythrocyte sedimentation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| albumin;total protein; | — |
Countries
China
Contacts
Public ContactChen Shi
Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
Outcome results
None listed