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Effect and mechanism of micro negative pressure therapy on burn wound: a randomized controlled trial.

Effect and mechanism of micro negative pressure therapy on burn wound through Rho/ROCK signal pathway

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033786
Enrollment
Unknown
Registered
2020-06-12
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn

Interventions

Control Group:Dressing by Mupirocin Ointment
MNP group:Dressing by MNPDD

Sponsors

The 903rd Hospital of PLA
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients treated in the clinical experimental center of the project from June 1, 2020 to May 31, 2023; 2. Patients diagnosed as burn; 3. Patients with mixed deep burn of II degree or with II degree; 4. The injury factors include patients with flame, hot water, steam, metal, etc., but excluding chemical burns such as acid, alkali, ammonia and electric injuries; 5. Patients with burn area <= 10% TBSA; 6. Patients aged 14-65 years old with unlimited gender; 7. Patients whose wounds need dressing change confirmed by clinicians; 8. Patients who agreed to participate in the study and signed a written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with life-threatening basic diseases, such as high-risk coronary heart disease; 2. Patients with diabetes, hypertension, autoimmune diseases and other basic diseases that significantly affect wound healing; 3. Patients who can't cooperate well, such as those with mental illness, or those with poor compliance; 4. Patients with known allergic history or allergic constitution (allergic to 2 or more allergens) to the ingredients or other chemical structures contained in this product and the control; 5. Pregnant or lactating women and those with fertility plans; 6. Patients who participated in other clinical studies within one month before inclusion; 7. Patients who cannot be followed up for a long time; 8. Patients who are considered by other researchers to be unsuitable for clinical research.

Design outcomes

Primary

MeasureTime frame
wound healing time;Wound healing rate;infection rate;Scar score;

Countries

China

Contacts

Public ContactJin Jian

The 903rd Hospital of PLA

jinjiannavy@163.com+86 13122680056

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026