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The probiotic Lactobacillus casei Shirota attenuates symptoms of vestibular migraine: a randomized placebo-controlled double-blind clinical trial

The probiotic Lactobacillus casei Shirota attenuates symptoms of vestibular migraine: a randomized placebo-controlled double-blind clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033771
Enrollment
Unknown
Registered
2020-06-11
Start date
2020-06-15
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vestibular migraine

Interventions

LcS:LcS
Placebo:Placebo

Sponsors

The Fourth Department of Neurology, Cangzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed as migraine according to the classification standard of International Headache Association; 2. Patients with moderate to severe vestibular migraine; 3. Patients with at least one migraine symptom, such as photophobia; 4. Patients with other causes have been excluded.

Exclusion criteria

Exclusion criteria: 1. Patients with bilateral vestibular dysfunction; 2. Patients with slight spontaneous vertigo caused by inactivity; 3. Patients with a history of neurological diseases; 4. Patients who had taken probiotics in the first two months of this study.

Design outcomes

Primary

MeasureTime frame
vestibular symptoms;—

Secondary

MeasureTime frame
anxiety and depressive symptoms;—

Countries

China

Contacts

Public ContactXiaoyuan Qi

The Fourth Department of Neurology, Cangzhou Central Hospital

qxy13888921283@sina.com+86 13333367986

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026