Large vessel occlusion stroke
Conditions
Interventions
Observation Group:Endovascular treatment
Sponsors
Department of Neurology, Maoming people's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients over 18 years old; 2. The patients with the level of aspects lower than 6 on the plain CT scan; 3. CTA / MRA / DSA confirmed the occlusion of the large vessels (whole internal carotid artery, M1 or M2 middle cerebral artery) in the internal carotid system; 4. Patients whose time from normal to admission (standard drug treatment group) / puncture time (intravascular treatment group) does not exceed 24 hours; 5. Informed consent has been signed by patients or their legal representatives; 6. Subjects and legal representatives are willing to follow up the follow-up requirements of the program.
Exclusion criteria
Exclusion criteria: 1. Patients with Mrs > 2 before onset; 2. Blood glucose 22.2mmol/l; 3. If any of the following exclusion criteria appears in the patient's image, it is not suitable to participate in this study; (1) Preoperative CT or MR showed bleeding symptoms; (2) CT or MR showed intracranial space occupying or tumor requiring surgical treatment; (3) Angiography showed simultaneous acute occlusion of multiple systems in bilateral carotid or basilar arteries. 4. Patients with heart, lung, liver and kidney failure or other serious diseases; 5. Patients with platelet count < 80x10^9/L; 6. Patients with life expectancy less than 3 months; 7. Patients who refuse to sign the consent of relevant research; 8. Select patients who still participate in clinical trials of other drugs or devices within 30 days before the visit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of good neurological function at 90 days (mRS <=3 defined as good prognosis); | — |
Secondary
| Measure | Time frame |
|---|---|
| mRS at 90 days (mRS 0-2);Changes of 24h NCCT ASPECTS after operation;5-7 days CTA/MRA postoperative success rate of recanalization; | — |
Countries
China
Contacts
Public ContactGeng Liao
Department of Neurology, Maoming people's Hospital
Outcome results
None listed