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Donor HLA genotyping by next generation sequencing of DNA from urine-derived cells of renal allograft recipients

Donor HLA genotyping by next generation sequencing of DNA from urine-derived cells of renal allograft recipients

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000033735
Enrollment
Unknown
Registered
2020-06-11
Start date
2018-06-01
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Transplantation

Interventions

Gold Standard:High Resolution HLA Typing Results of Donors and Receptors
Index test:HLA&#32
Results&#32
of&#32

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Kidney transplant recipients followed up in our center; 2. Kidney transplantation from deceased donor or living-related donors; 3. HLA-SSO or HLA-SBT typing data of the donor and the recipient is available; 4. Primary kidney transplantation; 5. Agree to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Double Kidney Transplantation, or Multiple Kidney Transplantation; 2. Combined with other organ transplants; 3. Combined with urinary tract infection.

Design outcomes

Primary

MeasureTime frame
HLA high resolution typing;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactWang Changxi

The First Affiliated Hospital of Sun Yat-sen University

wangchx@mail.sysu.edu.cn+86 13600450862

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026