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The effect of chewing gum on sore throat after thyroidectomy: a randomized controlled trial

The effect of chewing gum on sore throat after thyroidectomy: a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033704
Enrollment
Unknown
Registered
2020-06-09
Start date
2020-12-02
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative sore throat

Interventions

Swallowing group:Perform saliva swallowing twice before tracheal intubation
Chewing Gum Group 1:Chew a piece of chewing gum before endotracheal intubation for 2min
Chewing Gum Group 2:Chew two piece of chewing gum before endotracheal intubation for 2min

Sponsors

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status I or II patients who were 18–65 years of age with body mass index (BMI) <30 and who were undergoing elective total thyroidectomy surgery.

Exclusion criteria

Exclusion criteria: 1. Parenchymal carcinoma of the thyroid greater than 2 cm; 2. Thyroid cancer with thyroid enlargement or extension of the thyroid; 3. Preoperative throat pain, hoarseness, dysphagia, asthma, gastroesophageal reflux, impaired pharyngeal or esophageal function, or oral or Pharyngeal surgery history; 4. Inadequate language comprehension; 5. Phenylketonuria (contraindications for the sweetener aspartame in chewing gum); 6. Full mouth maxillary or lower dentures (cannot chew gum); 7. Recent use of non-steroidal anti-inflammatory drugs, there was a history of upper respiratory tract infection, smoking in the past week, or steroid treatment within 2 weeks before surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of NRS score of sore throat >3 scores at 24h after operation;

Secondary

MeasureTime frame
NRS score of sore throat at 1h ,24h and 48h after operation;The incidence of postoperative nausea and vomiting;The incidence of hoarse voice after surgery;Incidence of postoperative cough;Incidence of postoperative dysphagia;Incidence of blood in sputum after operation;

Countries

China

Contacts

Public ContactDunyi Qi

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University

qdy6808@163.com+86 15162159886

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026