The incidence, risk factors and clinical outcome of cytomegalovirus reactivation in patients with sepsis-related ARDS

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000033688

Enrollment

Unknown

Registered

2020-06-09

Start date

2020-07-01

Completion date

Unknown

Last updated

2020-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory and Critical Medicine

Interventions

HCMV reactivation group:Nil

HCMV non-reactivation group:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Meets the diagnostic criteria for sepsis; (2) Meets the ARDS diagnostic criteria; (3) Sign informed consent; (4) Aged >=18 years.

Exclusion criteria

Exclusion criteria: (1) Patients who are pregnant or lactating; (2) Serum HCMV serology (HCMV IgG) negative; (3) HCMV reactivation already exists at the time of transfer; (4) Expected survival time < 72h; (5) Antiviral drugs used before transfer to ICU; (6) Neutropenia (total leukocytes <1000/µL or neutrophils <500/µL) in ICU).

Design outcomes

Primary

Measure	Time frame
Laboratory-related indicators;Clinically relevant indicators;HCMV DNA;Positive rate of HCMV IgG;	—

Countries

China

Contacts

Public ContactZhihui Zhang

The First Affiliated Hospital of Guangzhou Medical University

pspaii@sina.com+86 13533102092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026