Ischemia-free kidney transplantation: a randomized open-label prospective clinical trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000033681

Enrollment

Unknown

Registered

2020-06-09

Start date

2020-07-01

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uremia

Interventions

experimental group:ischemia free kidney transplantation

control group:convetional kidney transplantation

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: (1) The donor age is between 14 and 60 years old, and the recipient age is between 18 and 70 years old. (2) Donors from brain death in China (3) Donor kidneys have acute kidney function injury, or kidneys from expanded criteria donor(ECD) (4) Primary kidney transplantation (5) Recipients and the relatives agree to receive ischimia free kidney transplantation and sign informed consent.

Exclusion criteria

Exclusion criteria: (1) Combined or multi-organ transplantation (2) Not suitable for machine perfusion due to severe variation of renal artery.

Design outcomes

Primary

Measure	Time frame
Incidence of delayed graft function;Serum creatinine and cystatin levels;NGAL, KIM-1, GST, L-FABP levels in the perfusion solution;Creatinine clearance during perfusion;Incidence of complications;	—

Secondary

Measure	Time frame
graft survival rate and receptor survival rate;	—

Countries

China

Contacts

Public ContactXiaoshun He

The First Affiliated Hospital of Sun Yat-Sen University

gdtrc@163.com+86 13802510799

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026