local allergic rhinitis
Conditions
Interventions
experimental group: subcutaneous immunotherapy
Sponsors
The First People's Hospital of Foshan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 5 to 60 years old patients; 2. with persistent or intermittent nasal symptoms like nasal itch, paroxysmal sneezing, nasal watery secretion and obstruction; 3. negative results of skin prick test and serum sIgE test, positive to houst dust mite in nasal allergen provocation test. Allergens in skin prick test are house dust mite, Dermatophagoides farine tropical mite, cat dander, dog dander, cocroach, mold and pollen. The type of allergens in the serum sIgE test is the same with skin prick test.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Severe or uncontrolled asthma, (FEV1 <70% of expected value) and irreversible obstructive airway diseases; 3. Combined with hypertension, coronary heart disease who are not suitable for adrenaline-treated diseases; 4. Severe immune diseases; 5. Severe psychological disorders or patients unable to understand the risks and limitations of treatment; 6. Malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| symptom score;medication score;living quality score;nasal allergen provocation test;adverse effect; | — |
Countries
China
Contacts
Public ContactQingqing Yu
81 Lingnan Avenue North, Chancheng District, Foshan, Guangdong
Outcome results
None listed