Sleep disorders
Conditions
Interventions
sleep disorder and nervous system development disorder group:External counterpulsation
Health control group:External counterpulsation
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 25-45 years old; 2. The subjects voluntarily participated in the study and signed the informed consent form by themselves or their legal guardian; 3. The patients with sleep disorder and nervous system development disorder were definitely diagnosed by clinical scale; 4. Normal hearing; 5. Normal vision; 6. IQ > 80; 7. Han nationality; 8. Be able to concentrate; 9. Normal activities of left and right hands; 10. Visual Auditory scale: over 90% familiarity. Other clinical cases were recorded normally.
Exclusion criteria
Exclusion criteria: 1. There are other neurodevelopmental disorders: Intelligence disorders, attention deficit / hyperactivity disorders, communication disorders, specific learning disorders, motor disorders, tic disorders and other types; 2. The following conditions (including but not limited to): neurological and physiological disorders, prenatal, perinatal and postnatal abnormalities, chromosomal diseases and metabolic diseases; Contraindications of treadmill exercise test: according to the guidelines of ACC / AHA ECG exercise test (treadmill exercise test) in 2009; Severe valvular disease, including moderate to severe aortic insufficiency, severe aortic stenosis, severe mitral stenosis and insufficiency; Aortic dissection aneurysm; Severe pulmonary hypertension (mean pulmonary artery pressure > 50mmhg); All kinds of bleeding diseases or bleeding tendency, or anticoagulant, INR > 2.0; Congenital heart disease and hypertrophic cardiomyopathy; Active phlebitis and lower extremity deep vein thrombosis; Severe atherosclerotic obliteration of lower extremity There were infection foci in the limbs; Uncontrolled hypertension (> 180 / 110mmhg); Uncontrolled tachyarrhythmias include frequent ventricular premature beats and ventricular tachycardia. However, patients with AF still benefit; Severe left heart failure (NYHA grade III-IV, ejection fraction = 40%); Pregnancy patients; Failing to sign the informed consent; 3. Previous sufferings: craniocerebral trauma, disturbance of consciousness, epilepsy, more serious cerebral ischemia or cerebral hemorrhage; 4. The subjects had a history of alcohol, drug or mental illness; 5. The subject has participated in any other clinical study within 3 months before joining the clinical study; 6. The researcher believes that there are other circumstances that the subjects are not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI imaging;clinical sleep assessment scale;clinical fatigue assessment scale;EEG;ECG;blood pressure;blood oxygen saturation;respiratory; | — |
Countries
China
Contacts
Public ContactShijun Li
Chinese PLA General Hospital
Outcome results
None listed