Endocardial Radiofrequency Septal Ablation Versus Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy

Endocardial Radiofrequency Septal Ablation Versus Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: a Randomized, Controlled, Open-Label Non-Inferiority Study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000033626

Enrollment

Unknown

Registered

2020-06-07

Start date

2020-06-01

Completion date

Unknown

Last updated

2020-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophic Obstructive Cardiomyopathy

Interventions

diofrequency ablation:radiofrequency ablation

Alcohol Ablation:Alcohol Septal Ablation

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years; 2. Symptomatic patients with HOCM; 3. LVOT gradient >= 50mmHg; 4. Heart function II-IV; 5. The thickness of IVS > 15mm; 6. Volunteer to participate in the study, sign informed consent and complete follow-up.

Exclusion criteria

Exclusion criteria: 1. End-stage of heart failure; 2. MI, CABG, PCI in the past 3 months; 3. Aortic stenosis; 4. Intracardiac thrombus; 5. Pregnant or nursing women; 6. Intolerant of exercise test (inducing malignant arrhythmia) or taking drugs affecting exercise test; 7. Life expectancy of other diseases < 1 year; 8. Refusing to participate in the study or failing to complete the follow-up.

Design outcomes

Secondary

Measure	Time frame
operation related complications;cardiovascular death;Life quality score;	—

Primary

Measure	Time frame
relief of LVOT gradient;	—

Countries

China

Contacts

Public ContactPei Zhang

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

3407032@zju.edu.cn+86 13588702251

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026