Dementia after stroke
Conditions
Interventions
experimental group:traditional cognitive training combined with computerized cognitive training
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged 6) 10; the score test indicated that two cognitive domains were damaged; ADL was abnormal (over 75 years old >= 25, under 75 years old >= 23); 7. Patients with consistent caregivers (> 3 days / week).
Exclusion criteria
Exclusion criteria: 1. Patients with other pathological brain diseases, such as vascular malformation, tumor, abscess, encephalitis or other common non ischemic brain diseases (such as multiple sclerosis), found on CT or MRI; 2. Patients with other types of cognitive impairment (including Alzheimer's disease, Parkinson's disease, Lewy body dementia, etc.) have been diagnosed clearly in the past; 3. Patients with brain white matter high signal Fazekas grade > 2; 4. Patients with brain atrophy with GCA grade > 2; 5. Patients with severe liver or kidney dysfunction (ALT value > 2 times the upper limit of normal value or ast value > 2 times the upper limit of normal value; creatinine > 1.5 times the upper limit of normal value); 6. Patients with severe heart failure; 7. Patients with confirmed or proposed acute coronary syndrome; 8. Patients with high-risk arrhythmias, such as: second or third degree atrioventricular block in sick sinus syndrome, tachycardia related syncope and atrial fibrillation caused by no pacemaker; 9. Other planned surgical operations or treatments may require termination of clinical observation; 10. Patients with severe non cardiovascular and cerebrovascular diseases whose expected survival time is less than 1 year; 11. Patients who are unable to understand and / or obey the research procedures and / or follow-up due to mental disorders and emotional disorders; 12. Patients with severe anxiety and depression (HAMD > 24, HAMA >= 29); 13. Patients with aphasia, blindness and deafness who are unable to complete neuropsychological assessment and other patients who are not considered suitable for the study by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE;MoCA;Video EEG plus flash stimulation;DTI; | — |
Countries
China
Contacts
Public ContactChuanqiang Qu
Shandong Provincial Hospital
Outcome results
None listed