Pulmonary protection
Conditions
Interventions
experimental group:Dexmedetomidine
control group:Normal saline
Sponsors
Deparment of Anesthesiology, the Affiliated Hospital of Nantong University
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. 70 patients with localized pulmonary masses underwent selective lobectomy; 2. Gender is not limited, ASA grade I-II; 3. Patients aged 20-70, body mass index (BMI) is 20-29kg / ?; 4. The ratio of forced expiratory volume to forced vital capacity (FEV1 / FVC) in the first second of pulmonary function test was more than 70%; 5. Patients without basic diseases of cardiopulmonary system, without any disease attack history, such as bronchospasm, asthma, etc.; 6. Patients able to understand and willing to participate in the study, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Patients who received immunotherapy or radiotherapy or chemotherapy before operation; 3. Patients with a history of allergy to dexmedetomidine; 4. Patients with bradyarrhythmia; 5. Patients with severe cardiopulmonary function, liver and kidney dysfunction; 6. Patients with severe snoring and obesity (BMI > 30 kg / m2); 7. Patients with history of digestive system diseases; 8. Patients with blood system diseases, asthma, hypertension, diabetes, mental disorders and mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ventilation index;The airway peak pressure;Airway resistance; | — |
Countries
China
Contacts
Public ContactWu Liuping
Deparment of Anesthesiology, the Affiliated Hospital of Nantong University
Outcome results
None listed