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Individualized Optimal Positive End-Expiratory Pressure on Perioperative Pulmonary Complications During Laparoscopic Colorectal Surgery in the elderly: a Randomized Controlled Trial

The application of lung ultrasound and driving pressure in evaluation of different ventilation protection strategies in prevention of atelectasis during laparoscopic colorectal surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033532
Enrollment
Unknown
Registered
2020-06-04
Start date
2020-06-08
Completion date
Unknown
Last updated
2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atelectasis

Interventions

Group 1:No
Group 2:PEEP 5cmH2O
Group 3:After pneumoperitoneum, give PEEP with pneumoperitoneum pressure + 2cmH2O, and perform manual lung recruitment every 30min (30cmH2O for 30s)

Sponsors

The First Affiliated Hospital of USTC Anhui Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. 60 patients are selected for endoscopic gastrointestinal surgery; 2. Patients aged 75 - 18 years; 3. Patients with BMI of 20-27 kg / m2; 4. ASA grade I-III, gender unlimited.

Exclusion criteria

Exclusion criteria: 1. Patients with abnormal liver and kidney function; 2. Patients with abnormal history of thorax; 3. Patients with cardiac insufficiency and severe lung disease (including FEV1 < 30% of the estimated value).

Design outcomes

Primary

MeasureTime frame
lung ultrasound;—

Secondary

MeasureTime frame
Arterial blood gas analysis;Hemodynamic parameters;—

Countries

China

Contacts

Public ContactLizhen Wang

The First Affiliated Hospital of USTC Anhui Provincial Hospital

ahwanglizhen@163.com+86 15155513602

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026