Spontaneous preterm birth
Conditions
Interventions
experimental group:history indicated cerclage
control group:expectant treatment and emergent cerclage
Sponsors
The First Maternal and Infant Health Care Hospital affiliated to Tongji University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The object of singleton pregnancy; 2. The object of abortion history in the second trimester of single pregnancy; 3. Subjects who visited our research center 8 weeks before pregnancy; 4. The person signing the informed consent.
Exclusion criteria
Exclusion criteria: 1. The object of fetal malformation; 2. Patients with iatrogenic premature delivery; 3. The subjects with LEEP or conization history; 4. The objects related to infection were identified in the previous abortion; 5. Patients with congenital uterine malformation or myoma >= 5 cm or multiple myoma; 6. Subjects with chronic diseases (such as hypertension, renal insufficiency, type I diabetes, some autoimmune diseases, etc.); 7. Patients with infectious diseases; 8. Patients with mental illness, etc..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rate of preterm birth < 34 weeks;delivery gestational week; | — |
Secondary
| Measure | Time frame |
|---|---|
| rate of preterm birth < 37 weeks;rate of preterm birth < 32weeks;rate of preterm birth < 30 weeks;rate of preterm birth < 28 weeks;neonatal birth weight;five minute Apgar score;NICU admission rate;neonatal IVH;neonatal ROP;neonatal PDA;neonatal BPD;NRDS;mechanical ventilation;neonatal NEC;neonatal sepsis;Composite neonatal morbidity/mortality;neonatal mortality; | — |
Countries
China
Contacts
Public ContactYing Hao
The First Maternal and Infant Health Care Hospital affiliated to Tongji University
Outcome results
None listed