sinonasal squamous cell carcinoma
Conditions
Interventions
Recurrence group vs non recurrence group:N/A
Sponsors
Eye, Ear, Nose & Throat Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
17 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate and sign an informed consent in writing. 2. Aged 18-70 years. Gender is not limited. 3. Primary sinonasal squamous cell carcinoma confirmed by pathology or cytology. 4. The clinical-stage was IVA-IVB. 5. There are tumor volumes that can be objectively measured or evaluated. 6. Karnofsky scores >= 70. 7. The estimated survival time is more than six months. 8. The blood routine, liver, renal function, and heart function are regular: WBC > 4.0 * 10^9/L, PLT >= 100 * 10^9/L, Hgb >= 100g/L; liver function: ALT, AST 1.5 times the upper limit of standard level, total bilirubin <= 1.5 times the upper limit of standard level; renal function: serum creatinine <= 1.5 times the upper limit of the standard level. 9. Childbearing age patients should take adequate contraceptive measures. 10. Those with proper compliance are expected.
Exclusion criteria
Exclusion criteria: 1. Malignant tumor with other parts. 2. With distant metastasis. 3. With a history of mental illness. 4. Bad habits or drug use. 5. Within one month before the test, patients who have participated in other clinical trials. 6. There was previous history of allergy to biological agents or other severe history of allergy, or allergic constitution. 7. Pregnant and lactating patients, those in the childbearing period who did not take adequate contraceptive measures, and 8. Researchers think that they should not participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical efficacy (CR, PR, SD, PD); | — |
Secondary
| Measure | Time frame |
|---|---|
| Survival evaluation (OS, PFS, DFS); | — |
Countries
China
Contacts
Public ContactXinmao Song
Eye, Ear, Nose & Throat Hospital of Fudan University
Outcome results
None listed