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Effect of early activity combined with early nutrition on acquired weakness in ICU patients

Effect of early activity combined with early nutrition on acquired weakness in ICU patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033482
Enrollment
Unknown
Registered
2020-06-02
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICU-acquired weakness

Interventions

Group 2:early nutrition and early mobilization

Sponsors

Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients aged >= 18 years; 2. Patients who are admitted to ICU for the first time; 3. Patients who are expected to stay in ICU for more than 72 hours; 4. The patients who are conscious and can respond to at least 3 simple commands clearly: open or close eyes, look at me, extend tongue, nod, frown; 5. Informed consent of patients or their agents.

Exclusion criteria

Exclusion criteria: 1. Patients with incomplete limbs; 2. Patients with neuromuscular diseases, such as myasthenia gravis, Guillain Barre syndrome, amyotrophic lateral sclerosis; 3. Patients with abnormal intracranial or spinal cord conditions that affect motor function (such as intracranial pressure rise, stroke moderate); 4. Patients who have had gastrointestinal surgery within one month; 5. Patients with hyperthyroidism and other endocrine diseases affecting nutrition and metabolism; 6. Patients who are expected to be unable to carry out nutritional support within 48 hours after staying in ICU; 7. Pregnancy; 8. Patients with advanced cancer; 9. Patients with poor prognosis or short-term death.

Design outcomes

Primary

MeasureTime frame
MRC sum-score;

Secondary

MeasureTime frame
SOFA score;BI;time of ICU stay;Duration of mechanical ventilation;ICU mortality;

Countries

China

Contacts

Public ContactYuying Fan

School of Nursing, Harbin Medical University,

fanfanfensituan@126.com+86 13603630368

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 18, 2026