Type II diabetes with neuropsychiatric or mental disease
Conditions
Interventions
Anxiety Disorder:???
Type II diabetes with anxiety:Nil
Type II diabetes with Alzheimer's:no
Type II diabetes with sleep disorders:Nil
Type II diabetes with depression:Nil
Alzheimer's disease:Nil
Sponsors
Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetes inclusion criteria (1) refer to the American Diabetes Association Criteria: fasting blood glucose >=7.0 mmol/L (126 mg / dL), postprandial blood glucose >=11.1 mmol/L (200 mg/dL); (2) Have a clear history of diabetes; (3) Aged >=30 years old; (4) Clear consciousness, no intellectual disability, and normal communication. The inclusion criteria for neuropsychiatric disorders are based on the "Chinese Classification and Diagnostic Criteria for Mental Disorders, Third Edition" (CCMD-3): 2. Alzheimer's disease (1) Meet the diagnostic criteria for organic mental disorders; (2) Comprehensive intelligence damage; (3) No sudden stroke-like attack, no signs of focal nervous system damage in the early stage of the disease; (4) No clinical or special examination indicates that the intellectual impairment is caused by other physical or brain diseases; (5) The following characteristics may support diagnosis but are not essential: 1) Impaired advanced cortical function, may include aphasia, loss of recognition, and uselessness; 2) Indifference, lack of active activities, or irritability and uncontrolled social behavior; 3) Parkinson's symptoms and seizures may occur in advanced severe cases; 4) Somatic, nervous system, laboratory tests can prove brain atrophy; (6) Neuropathological examination helps to confirm the diagnosis. 3. Sleep disorders: (1) Almost insomnia is the only symptom, including difficulty falling asleep, not sleeping deeply, dreaming, waking up early, or not being able to sleep after waking up, discomfort after waking up, fatigue, or drowsiness during the day, etc.; (2) Has the advantage of insomnia and extreme attention to the results of insomnia. 4. Depression: Mainly low mood, and at least the following four items: (1) Loss of interest, no sense of happiness; (2) Loss of energy or fatigue; (3) Psychomotor retardation or agitation; (4) Low self-evaluation, self-blame, or guilt; (5) Difficulty in associating or decreased ability to think consciously; (6) Repeated thoughts of wanting to die or commit suicide or self-harm; (7) Sleep disorders, such as insomnia, early wake up, or excessive sleep; (8) Decreased appetite or weight loss; (9) Decreased libido. 5. Anxiety (1) Meet the diagnostic criteria of neurosis; (2) Mainly with persistent primary anxiety symptoms and meeting the following 2 items: 1) frequent or continuous fear or fearlessness with no clear subject or fixed content; 2) with autonomic symptoms or motor disturbance (3) Severe criteria: The social function is impaired, and the patient is suffering because it is unbearable and unrelievable. (4) Criteria for disease course: at least 6 months after meeting the symptom criteria Criteria for diagnosis of panic disorder: (1) There is no obvious cause for the attack, and there is no specific situation related to it. The attack is unpredictable; (2) In the intermittent period, there is no obvious symptoms except for fear of recurrence; (3) Strong fear, anxiety, and obvious autonomic symptoms at the time of the attack, and often painful experiences such as disintegration, reality disintegration, fear of dying, or a sense of loss of control; (4) The seizure started suddenly and reached a peak quickly. The consciousness was clear during the seizure and can be recalled later. (5) Severe criteria: The patient is suffering because it is unbearable and unrelievable; (6) Criteria of disease course: at least 3 panic attacks w
Exclusion criteria
Exclusion criteria: (1) Normal blood glucose <5.6 mmol / L (100 mg / dL), standard 75 g glucose tolerance test 2 h after OGTT blood glucose <7.8 mmol / L (140 mg / dL) (2) Transient blood glucose increase caused by other stress factors; (3) Severe cardiovascular, liver and kidney dysfunction; (4) HIV positive, pregnancy, cancer, severe infection; (5) Type 1 diabetes, gestational diabetes and special diabetes; (6) Incomplete biochemical test indicators and electronic medical record information; (7) Exclude patients with cancer and tumor after coronary stent implantation; (8) Exclude psychiatric disorders such as overdose of excitatory drugs, hypnotic sedative drugs, or medications for mental illness, obsessive-compulsive disorder, phobia, suspected illness, neurasthenia, mania, depression or schizophrenia; (9) Women who are pregnant or breastfeeding; (10) Those who refuse to investigate or do not cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SBP; | — |
Countries
China
Contacts
Public ContactYubo Li
Tianjin University of Traditional Chinese Medicine
Outcome results
None listed