A noninferiority, multicentre randomised, 6-month comparative effectiveness, clinical trial protocol of manipulation under anesthesia compared to lysis of adhesions

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000033467

Enrollment

Unknown

Registered

2020-06-01

Start date

2020-11-01

Completion date

Unknown

Last updated

2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthrofibrosis after arthroscopic knee surgery

Interventions

manipulation under anesthesia group:manipulation under anesthesia

lysis of adhesions group:lysis of adhesions

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients 12-24 weeks after unilateral knee arthroscopy; 2. Patients with knee joint active flexion < 110 degrees; 3. Patients with limited knee extension < 5 degrees.

Exclusion criteria

Exclusion criteria: 1. Patients with postoperative joint infection; 2. Patients with heterotopic ossification, graft dislocation or prosthesis loosening; 3. Patients with knee injury and other joint (hip or ankle) injury of lower extremity; 4. Patients with injury or operation history of the contralateral knee joint; 5. Patients with other diseases affecting lower extremity function; 6. Patients with re adhesion after arthroscopic release.

Design outcomes

Primary

Measure	Time frame
knee flexion;	—

Secondary

Measure	Time frame
International Knee Documentation Committee, IKDC;Lysholm scale;Tegner Activity Score;	—

Countries

China

Contacts

Public ContactCai Bin

School of Medicine, Shanghai Jiaotong University

shrehab@163.com+86 15618738497

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026