type 2 diabetes mellitus with obesity
Conditions
Interventions
loop anastomosis group:receiving loop sleeve gastrectomy combined with duodenaljejunal bypass
Roux-en-Y anastomosis group:receiving Roux-en-Y sleeve gastrectomy combined with duodenaljejunal bypass
Sponsors
The First Affliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patient with T2DM aged 20 to 60 years old, the duration of disease less than 15 years, and the fasting C peptide level is greater than the minimum reference value, and meets one of the following conditions: 1. T2DM patients with BMI>=32.5 and poor control of blood glucose (HbA1c> 7.0%), who are managed by the diet control of the nutrition department, other life styles and optimized medical control regulated by the endocrinology department for more than half a year; 2. T2DM patients with BMI 27.5 to 32.5, poor control of blood glucose (HbA1c> 7.0%) and other cardiovascular risk factors such as high TG and low HDL -C, high blood pressure, or those with diabetes complications, who are managed by the diet control of the nutrition department, other life styles and optimized medical control regulated by the endocrinology department for more than half a year.
Exclusion criteria
Exclusion criteria: 1. T1DM, LADA, gestational diabetes and other special types of diabetes; 2. Preoperative diagnosis of GERD; 3. Drug or alcohol addiction or suffering from uncontrollable mental illness; 4. Those with intellectual disability or immature treatment, whose behavior cannot be controlled; 5. Those who have unrealistic anticipation of the surgery; 6. Unwilling to bear the risk of potential complications of surgery; 7. Those who can not cooperate with postoperative diet and lifestyle changes, and have poor compliance; 8. Those who have poor general condition and are unable to tolerate general anesthesia or surgery; 9. Disagree with participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| remission rate of type 2 diebetes mellitus; | — |
Countries
China
Contacts
Public ContactHui Liang
The First Affliated Hospital of Nanjing Medical University
Outcome results
None listed