Effect of postoperative dexmedetomidine sedation on the incidence of delirium

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000033436

Enrollment

Unknown

Registered

2020-05-31

Start date

2020-06-15

Completion date

Unknown

Last updated

2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

delirium

Interventions

1:dexmedetomidine

2:propofol

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients returning to ICU after CABG surgery for endotracheal intubation requiring sedation; Aged 40 years or higher.

Exclusion criteria

Exclusion criteria: 1. Preoperative schizophrenia, epilepsy, Parkinson's disease, severe dementia; 2. Preoperative attention to hearing impairment and language impairment can not communicate; 3. Craniocerebral injury or functional neurosurgical operation history; 4. Preoperative patients with pathological sinus node syndrome, severe sinus bradycardia (heart rate <50 beats/min), and degree II or above atrioventricular block without pacemaker implantation; 5. Postoperative severe bradycardia (heart rate <50 beats/min) or grade III atrioventricular block without temporary pacemaker; 6. Severe liver and kidney failure; 7. Cardiopulmonary resuscitation or secondary surgery was performed during the treatment.

Design outcomes

Secondary

Measure	Time frame
Duration of delirium;RASS;Propofol dosage;S-100ß;MESS;	—

Primary

Measure	Time frame
Delirium incidence;	—

Countries

China

Contacts

Public ContactHong Liu

Fuwai Hospital

lhfuwai@sina.com+86 13161006247

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026