major depressive disorder
Conditions
Interventions
Healthy control group:none
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
No minimum to 60 Years
Inclusion criteria
Inclusion criteria: Patient group: Under 60 years old, right-handed, elementary school or above education level, IQ> 85, head movement during MRI scan is not more than 2mm, as determined by imaging physicians, there is no organic brain structure abnormality, which is in accordance with DSM-V depression Diagnostic criteria, can understand the contents of the scale, have not received electrical convulsions, patient themselves and their family members have informed consent and voluntarily participated in this study. Healthy control group: Under 60 years old, right-handed, elementary school or above education level, IQ> 85, head movement during MRI scan is not more than 2mm, as determined by imaging doctors without organic brain structure abnormalities, can understand the scale Contents, have not taken any psychoactive drugs, have not taken any other drugs recently, have no major or chronic physical diseases, and have a negative family history of mental disorders, controls themselves and their family members have informed consent and voluntarily participated in this study.
Exclusion criteria
Exclusion criteria: Patient group: Patients with other Axis I and Axis II mental diseases, other physical diseases, neurological diseases or injuries, patients who have used psychoactive substances, pregnancy or lactation, and claustrophobia are excluded. Healthy control group: Coexisting other Axis I and Axis II mental diseases, suffering from other physical diseases, having a history of suicide attempts or a history of neurological diseases or injuries, people who have used psychoactive substances, pregnancy or lactation, and claustrophobia are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Environmental factor assessment;Magnetic Resonance Imaging;Genome-wide genetic data;intestinal flora;Blood, urine and fecal metabolites were analyzed based on omics;electroencephalogram; | — |
Countries
China
Contacts
Public ContactYin Li
West China School of Clinical Medicine, Sichuan University
Outcome results
None listed