The mechanism of male infertility induced by abnormally expression of clock

Study on the role and its molecular mechanism of lysine succinylation in the reduced male fertility caused by down-regulation of testicular Clock gene

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000033393

Enrollment

Unknown

Registered

2020-05-30

Start date

2020-07-01

Completion date

Unknown

Last updated

2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male infertility

Interventions

Obstructive azoospermia:None

No obstruction with spermatorrhea:None

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. Age unlimited; 2. Male patients who are clinically diagnosed with idiopathic infertility.

Exclusion criteria

Exclusion criteria: 1. Intratesticular infection; 2. Testicular fibrosis; 3. Cryptorchidism or anerchism.

Design outcomes

Primary

Measure	Time frame
Expression of clock gene in testis;Succinylation level of sperm protein;Serum marker;	—

Countries

China

Contacts

Public ContactCheng Shuting

West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University

664543989@qq.com+86 15528330028

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026