Effects of spinal anesthesia and 5-HT3 receptor antagonist on postoperative intestinal exhaust in patients undergoing cesarean section: a randomized controlled trial.

Effects of spinal anesthesia and 5-HT3 receptor antagonist on postoperative intestinal exhaust in patients undergoing cesarean section

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000033389

Enrollment

Unknown

Registered

2020-05-30

Start date

2020-05-30

Completion date

Unknown

Last updated

2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delayed bowel exhaust after caesarean section

Interventions

Group B:0.75% bupivacaine 1.0ml back to 1.5ml bolus injection

Group C:0.75% bupivacaine 1.2ml back to 2.4ml bolus injection

Group D:Azazatron 10mg

Group A:0.75% bupivacaine 1.0ml back to 2.0ml bolus injection

Eligibility

Sex/Gender

Female

Age

22 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Full term pregnant women aged 22-40; 2. The parturients with ASA grade I ~ II were 155 ~ 170cm in height and 60 ~ 80kg in weight; 3. Patients are willing to use postoperative analgesia pump.

Exclusion criteria

Exclusion criteria: 1. Patients with failure of combined spinal and epidural anesthesia; 2. Patients with poor cerebrospinal fluid return or subdural puncture needle breaking into the subarachnoid space. 3. Those without obstetric complications; 4. Subjects with serious systemic diseases; 5. Subjects with important organ dysfunction; 6. Subjects with contraindications of intraspinal anesthesia.

Design outcomes

Primary

Measure	Time frame
Postoperative first exhaust time;	—

Countries

China

Contacts

Public ContactLiu Meiyu

Affiliated Hospital of Yangzhou University

myliu@yzu.edu.cn+86 13511758157

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026