Chronic heart failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 24 elderly patients with chronic heart failure admitted to the Department of Cardiology of our hospital; 2. The diagnostic standard of chronic heart failure was Framingham heart failure (1971); 3. All patients were fed a low salt and low fat diet; 4. According to the 2018 China heart failure guidelines, patients who receive standard drug treatment, including sakubatrevalsartan, ß receptor blocker, diuretic, aldosterone receptor antagonists, are given antiarrhythmic drugs or drugs to control ventricular rate as required; 5. All patients need to sign informed consent; 6. Inclusion criteria: (1) Aged >= 60 years; (2) Chronic heart failure, NYHA II-III; (3)NT-proBNP >= 600pg/ml.
Exclusion criteria
Exclusion criteria: 1. Patients with acute attack or acute heart failure of chronic heart failure; 2. Patients with acute coronary syndrome within 6 months; 3. Patients with infection, malignant tumor, obvious primary diseases of liver and kidney, and autoimmune diseases; 4. Patients with pericardial tamponade, pulmonary embolism and refractory end-stage heart failure; 5. Patients with gastrointestinal diseases or malabsorption and malnutrition (MNA-SF 0-7 points) were assessed by mini nutrition scale; 6. Patients combined with antibiotics or probiotics; 7. Patients who died within 72 hours after admission; acute myocardial infarction; active myocarditis; cardiogenic shock; severe ventricular arrhythmia; patients with allergic constitution; 8. Other patients: such as respiratory diseases, cerebral vascular embolism, migraine, etc. may affect the intestine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora;TMAO; | — |
Countries
China
Contacts
Zhejiang Hospital