A self-control study of intestinal flora changes in children with idiopathic precocious puberty before and after treatment

Relationship between idiopathic precocious puberty and intestinal flora

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000033305

Enrollment

Unknown

Registered

2020-05-27

Start date

2020-05-31

Completion date

Unknown

Last updated

2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic precocious puberty

Interventions

Treatment response group vs.non-response group:GnRHa treatment

Eligibility

Sex/Gender

All

Age

1 Years to 16 Years

Inclusion criteria

Inclusion criteria: 1. According to the diagnostic criteria of idiopathic precocious puberty, the clinical criteria of precocious children are the early appearance of the second sex sign, the acceleration of linear growth, the advance of bone age, the increase of gonad and the activation of HPGA function; 2. Cases of idiopathic precocious puberty were screened out.

Exclusion criteria

Exclusion criteria: The interference caused by malignant tumor, dysplasia of digestive tract, immune deficiency diseases, drugs and other factors shall be excluded.

Design outcomes

Primary

Measure	Time frame
gut microbiota;	—

Countries

China

Contacts

Public ContactCongfu Huang

Shenzhen Longgang District Maternal and Child Health Hospital

78333755@qq.com+86 15814693069

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026