Effect of chicory on cardiovascular health in adult men with overweight: a randomized controlled trial.

Effect of chicory on cardiovascular health in adult men with overweight

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000033291

Enrollment

Unknown

Registered

2020-05-27

Start date

2020-06-01

Completion date

Unknown

Last updated

2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular diseases

Interventions

1:Chicory leaf juice (chicory leaf 150g), washing out for one week, chicory root juice (peeled chicory root 40g), washing out for one week, distilled water (soluble starch 7.3g), washing out for one w

2:Chicory root juice (peeled chicory root 40g), washing out for one week, distilled water (soluble starch 7.3g), washing out for one week, chicory leaf juice (chicory leaf 150g), washing out for one

3:Distilled water (soluble starch 7.3g), washing out for one week, chicory leaf juice (chicory leaf 150g), washing out for one week, chicory root juice (peeled chicory root 40g), washing out for one w

4:Chicory leaf juice (chicory leaf 150g), three months

5:Chicory root juice (peeled chicory root 40g), three months

6:Distilled water (soluble starch 7.3g), three months

Eligibility

Sex/Gender

Male

Age

30 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Male adults aged 30~45 years who signed informed consent; 2. BMI24-28kg/?; 3. smoking index less than 20 pack-years (smoking index = number of smoking branches per day×smoking years); 4. weekly alcohol consumption less than 175g; 5. weekly high-intensity exercise accumulation time less than 75 minutes or moderate-intensity exercise accumulation time less than 150 minutes; 6. normal blood routine (liver and kidney function, hemoglobin, hematocrit and leukocyte count); 7. no diabetes, hyperthyroidism, gout, autoimmune diseases.

Exclusion criteria

Exclusion criteria: 1. Individuals who took anti-inflammatory drugs, antibiotics, antihypertensive drugs, phytochemical dietary supplements within 3 months of the study; 2. individuals who had suffered from acute and chronic infectious diseases, malignant tumors, trauma, or surgery within 1 month prior to the trial.

Design outcomes

Primary

Measure	Time frame
SOD;GSH-Px;malonaldehyde;Brachial blood flow FMD;Blood lipids;Blood sugar;Renal function;Liver function;Blood cytokines;	—

Countries

China

Contacts

Public ContactDongliang Wang

Sun Yat-Sen University

wdliang@mail.sysu.edu.cn+86 18819154596

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026