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Yishentongluo Decoction in Treatment of Idiopathic Asthenozoospermia Infertility: study protocol for a Randomized Controlled Trial

Effect of Yishentongluo Decoction on mitochondrial membrane potential of spermatozoa in infertile patients with idiopathic asthenozoospermia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033290
Enrollment
Unknown
Registered
2020-05-27
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Sponsors

Henan Province Hospital of TCM
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
23 Years to 48 Years

Inclusion criteria

Inclusion criteria: 1.Males, aged between 23 and 48 years; 2.Patients diagnosed as infertility and idiopathic asthenospermia; 3.Patients diagnosed as kidney deficiency and blood stasis based on the TCM theory of syndrome differentiation; 4.Patients with normal sexual function, regular sexual life (the frequency of sexual life is required to be no less than 1 time / week); 5.Patients willing to participate in the study and sign an informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with infertility caused by diseases of reproductive system organs or female infertility; 2.Patients with MAR(+); 3.Patients with abnormal sex hormone, seminal plasma biochemistry and seminal plasma elastase; 4.Patients with infertility caused by erectile dysfunction,ejaculatory disorder unable to complete sexual intercourse; 5.Patients with reproductive system infection:including Chlamydia trachomatis and Mycoplasma positive; 6.Patients with a history of allergy to treatment drugs or allergic constitution; 7.Patients have taken drugs affecting the experimental study within 3 months; 8.Patients with mental illness,malignant tumors and serious organic diseases; 9.Patients who participated in other clinical trials in the past 3 months.

Design outcomes

Primary

MeasureTime frame
PR (%);

Secondary

MeasureTime frame
pregnancy rate (%);Mitochondrial membrane potential of sperm;PR+NP (%);Total effective sperm;

Countries

China

Contacts

Public ContactLipeng Fan

Henan Province Hospital of TCM

mlzy365@126.com+86 18860364416

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026