Knee arthritis
Conditions
Interventions
Group A:Preemptive analgesia with femoral nerve block
Group B:Praecoxib for preemptive analgesia
Group C:No preemptive analgesia
Group D:Nerve block combined with praecoxib for preemptive analgesia
Sponsors
Tthe First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients to receive TKA; 2. Patients with ASA grade I-III; 3. Age of patients: 18-85 years old; 4. Gender: both male and female; 5. Patients who are fully informed and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with uncontrolled hypertension and coronary heart disease; 2. Patients with mental disorders and cognitive impairment; 3. Patients with liver and kidney dysfunction; 4. Aspirin, sulfanilamide, non steroidal antipyretic, analgesic and anti-inflammatory drug allergy patients; 5. Patients with coagulation dysfunction and high risk of perioperative bleeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;Montreal Cognitive Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| C-reactive protein;NSE; | — |
Countries
China
Contacts
Public ContactJun Dong
Department of Anesthesiology, the First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed