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Peptidomics Profile Characterization and Diagnostic Model Construction of Heart Failure

Peptidomics Profile Characterization and Diagnostic Model Construction for Yang Deficiency Water Retention Syndrome of Heart Failure

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000033278
Enrollment
Unknown
Registered
2020-05-26
Start date
2021-01-01
Completion date
Unknown
Last updated
2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure

Interventions

Gold Standard:According to the level of ejection fraction (EF), heart failure can be divided into heart failure with reduced ejection fraction (HFrEF, EF 50%), and heart failure with Mid-Range ejecti

Sponsors

Hunan University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
40 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Meet the criteria of heart failure diagnosis in 2018 China heart failure diagnosis and treatment guidelines. 2. The State Administration of traditional Chinese Medicine issued TCM clinical pathway and TCM diagnosis and treatment plan (2017 version) for the TCM diagnosis and treatment plan of heart failure to carry out TCM syndrome differentiation and type diagnosis. 3. Adopt the new classification and diagnosis standard of heart failure. According to the level of ejection fraction (EF), heart failure can be divided into heart failure with decreased ejection fraction (hfref, EF 50%), and heart failure with ejection fraction in the critical range of 40% - 49% (hfmref).

Exclusion criteria

Exclusion criteria: 1. The elderly over 90 years old; 2. Patients with renal insufficiency; 3. Patients with malignant tumors.

Design outcomes

Primary

MeasureTime frame
Proteomics of plasma and urine;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactHao Liang

Hu'nan University of Chinese Medicine

lianghao@hnucm.edu.cn+86 13975863601

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026